Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899607 | 0.83 | NOTUM (0.32) | NOTUM | |
| SCHEMBL6899425 | 0.81 | NOS3 (0.33) | NOTUMNOS3NOS1NOS2 | |
| SCHEMBL13834431 | 0.81 | NOS3 (0.33) | NOTUMNOS3NOS1NOS2 | |
| SCHEMBL29991327 | 0.81 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL29991777 | 0.81 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL29991487 | 0.76 | — | — | |
| SCHEMBL7899513 | 0.73 | NOS3 (0.36) | NOTUMNOS3NOS1NOS2 | |
| SCHEMBL16519812 | 0.73 | PGR (0.33) | — | |
| SCHEMBL29991822 | 0.71 | NOS3 (0.34) | NOTUMNOS3NOS1NOS2 | |
| SCHEMBL16519791 | 0.71 | HCRTR2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509950-B1 | 5-Amino-4-hydroxypentoyl amides | JANSSEN R & D IRELAND (IE) | 2015-02-25 | — | — | EP | disclosed |
| WO-2011070131-A1 | 5-AMINO- 4-HYDROXYPENTOYL AMIDES | TIBOTEC PHARMACEUTICALS (IE) | 2011-06-16 | — | — | WO | disclosed |