Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835011 | 0.83 | UGT2B17 (0.32) | NOTUM | |
| SCHEMBL13834753 | 0.83 | UGT2B17 (0.32) | NOTUM | |
| SCHEMBL6900507 | 0.83 | NOTUM (0.32) | NOTUM | |
| SCHEMBL16519812 | 0.77 | PGR (0.33) | — | |
| SCHEMBL13197596 | 0.66 | LTB4R (0.31) | — | |
| SCHEMBL6900223 | 0.66 | KDM1A (0.32) | — | |
| SCHEMBL13197607 | 0.66 | LTB4R (0.31) | — | |
| SCHEMBL6897674 | 0.66 | AKR1B1 (0.38) | — | |
| SCHEMBL29991327 | 0.64 | NOS3 (0.33) | — | |
| SCHEMBL29991777 | 0.64 | NOS3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509950-B1 | 5-Amino-4-hydroxypentoyl amides | JANSSEN R & D IRELAND (IE) | 2015-02-25 | — | — | EP | disclosed |
| WO-2011070131-A1 | 5-AMINO- 4-HYDROXYPENTOYL AMIDES | TIBOTEC PHARMACEUTICALS (IE) | 2011-06-16 | — | — | WO | disclosed |