Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842507 | 0.88 | MAPK1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL57602 | 0.85 | — | — | |
| SCHEMBL29424769 | 0.85 | — | — | |
| SCHEMBL454111 | 0.85 | CA1 (0.81) | CA1CA2CA7CA9CA12 | |
| SCHEMBL727333 | 0.85 | ALDH1A1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30751956 | 0.84 | IDO1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL971122 | 0.83 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Ammonia Solution, Strong SCHEMBL4275178 | 0.83 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Phosphine SCHEMBL21796069 | 0.83 | CA1 (0.77) | CA1CA2CA7CA9CA12 | |
| Bromide SCHEMBL4665342 | 0.81 | CA1 (0.57) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443923-A1 | HYDROXY SUBSTITUTED AMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003037325-A1 | HYDROXY SUBSTITUTED AMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |