SCHEMBL727333

SCHEMBL727333

Brc1ccccc1Oc1ccccc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
HTR7 P34969 1/20 0.45
TTR P02766 1/20 0.42
LMNA P02545 2/20 0.42
TSHR P16473 1/20 0.41
LCK P06239 1/20 0.41
RAB9A P51151 2/20 0.38
GRM4 Q14833 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
HTR1A P08908 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842507 0.97 MAPK1 (0.46) ALDH1A1MAPK1TDP1L3MBTL1HTR7
SCHEMBL30274289 0.87 MAPK1 (0.39) ALDH1A1MAPK1TDP1L3MBTL1HTR7
SCHEMBL74839 0.86 ALDH1A1 (0.52) ALDH1A1MAPK1L3MBTL1HTR7LMNA
SCHEMBL2848211 0.85 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1L3MBTL1HTR7
SCHEMBL31690687 0.85 HTR1A (0.46) ALDH1A1MAPK1TDP1L3MBTL1HTR1A
SCHEMBL30379424 0.85 MAPT (0.52) ALDH1A1MAPK1TDP1L3MBTL1HTR7
SCHEMBL5548016 0.85 ALDH1A1 (0.38) ALDH1A1MAPK1TDP1L3MBTL1HTR7
SCHEMBL11818090 0.85 HPGD (0.48) ALDH1A1MAPK1TDP1L3MBTL1LMNA
SCHEMBL6900852 0.85 CA1 (0.59) ALDH1A1MAPK1TDP1L3MBTL1HTR7
SCHEMBL28857814 0.85 TSHR (0.48) ALDH1A1MAPK1L3MBTL1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075202-B Use of organooxyimide salts as flame retardants, flame-retardant plastic compositions, method for the production thereof and moulded parts, paints or coatings 弗劳恩霍弗应用研究促进协会 2020-06-16 CN claimed
CN-210410917-U Polybrominated phenylene ether detects uses reducing mechanism in fodder 上海市农业科学院 2020-04-28 CN claimed
CN-103420946-B A kind of separation method of epoxychloropropane 中国石油化工股份有限公司 2016-08-03 CN claimed
CN-100497281-C Method of preparing p-bromophenyl ether KENG ZONG (CN) 2009-06-10 CN claimed
CN-101012157-A Method of preparing p-bromophenyl ether ZONG KENG (CN) 2007-08-08 CN claimed
EP-0549188-B1 Reinforced flame-retarded polyester resin compositions GE PLASTICS JAPAN LTD (JP) 1997-06-04 EP claimed
US-5326806-A Reinforced flame-retardant polyester resin compositions GENERAL ELECTRIC COMPANY (US) 1994-07-05 US claimed
JP-2049756-A None JP disclosed
JP-63162759-A None JP disclosed
JP-3056451-A None JP disclosed
CN-120319340-A Relative content prediction method for copper-containing solid waste pyrolysis bromine-containing aromatic product 华北电力大学 2025-07-15 CN disclosed
WO-2024106207-A1 AQUEOUS DISPERSION OF SURFACE-HYDROPHOBIZED INORGANIC POWDER AND COSMETIC PREPARATION CONTAINING SAME 日光ケミカルズ株式会社 2024-05-23 WO disclosed
CN-110540545-B Organic electroluminescent device and monoamine compound for organic electroluminescent device 三星显示有限公司 2024-04-09 CN disclosed
JP-S63162759-A FLAME-RETARDANT POLYAMIDE ELASTOMER COMPOSITION UBE IND LTD 1988-07-06 JP disclosed
WO-1988000199-A1 NEW THIOPHOSPHATE ESTER; ALSO POLYURETHANE FOAM OR PREPOLYMER, CONTAINING TRIS- AND BIS- (2,4,6-TRIBROMOPHENOXY) (THIO) PHOSPHATE MAERSCHEL RICHARD JOHN (AU) 1988-01-14 WO disclosed
EP-0183047-A2 Process for the photochemical vapor depositiom of hetero-linked polymers Hughes Aircraft Company (US) 1986-06-04 EP disclosed
US-4547395-A OXYGEN, NITROGEN OR SULFUR PRECURSORS HUGHES AIRCRAFT COMPANY (US) 1985-10-15 US disclosed
EP-0129762-A2 Polyphenylene ether resin compositions containing halogenated aromatic compound alone as a flame retardant agent GENERAL ELECTRIC COMPANY (US) 1985-01-02 EP disclosed
US-RE29617-E Aryl methylene polymers prepared from chloral, bromal or glyoxalic acid GENERAL ELECTRIC COMPANY (US) 1978-04-25 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed