Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905206 | 1.00 | METAP1 (0.48) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31196693 | 1.00 | METAP1 (0.48) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6907672 | 0.92 | ALDH1A1 (0.50) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6905898 | 0.89 | ALDH1A1 (0.47) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29232849 | 0.89 | METAP1 (0.50) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6903501 | 0.86 | KDM4E (0.50) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17460809 | 0.86 | ALDH1A1 (0.48) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15308827 | 0.86 | ALDH1A1 (0.48) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29066845 | 0.86 | METAP1 (0.44) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4897556 | 0.86 | METAP1 (0.57) | METAP1MAPTSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |