SCHEMBL6907672

SCHEMBL6907672

Cc1ccc2c(c1)Cc1ccccc1C2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
DRD1 P21728 8/20 0.44
DRD5 P21918 8/20 0.44
DRD2 P14416 7/20 0.44
DRD3 P35462 6/20 0.44
METAP1 P53582 2/20 0.44
DRD4 P21917 6/20 0.43
CYP2A6 P11509 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903501 0.93 KDM4E (0.50) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL31196693 0.92 METAP1 (0.48) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL6905206 0.92 METAP1 (0.48) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL6901119 0.92 METAP1 (0.48) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL6902791 0.89 DRD1 (0.49) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL1609497 0.84 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL31400232 0.84 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL13979645 0.83 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL19810027 0.82 CYP2A6 (0.58) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2
SCHEMBL29232849 0.82 METAP1 (0.50) ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed