SCHEMBL6901265

SCHEMBL6901265

Oc1ccc(C=COC=Cc2ccc(O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.58
KDM4E B2RXH2 4/20 0.58
MAPT P10636 4/20 0.58
CA12 O43570 4/20 0.58
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA7 P43166 4/20 0.58
CA9 Q16790 4/20 0.58
CA14 Q9ULX7 4/20 0.58
TYR P14679 4/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP2C9 P11712 3/20 0.58
CA3 P07451 3/20 0.58
CA4 P22748 3/20 0.58
CA6 P23280 3/20 0.58
CA5A P35218 3/20 0.58
CA5B Q9Y2D0 3/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
MAOB P27338 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2770699 0.86 KDM4E (0.54) APPKDM4EMAPTCA12CA1
Phenol SCHEMBL563480 0.83 TDP1 (0.50) APPKDM4EMAPTCA12CA1
SCHEMBL10981021 0.80 APP (0.54) APPKDM4EMAPTCA12CA1
SCHEMBL976834 0.80 APP (0.54) APPKDM4EMAPTCA12CA1
SCHEMBL6266983 0.80 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL6266989 0.80 APP (0.74) APPKDM4EMAPTCA12CA1
Trans-4,4'-Dihydroxystilbene SCHEMBL491346 0.80 APP (0.74) APPKDM4EMAPTCA12CA1
SCHEMBL9678787 0.80 APP (0.74) APPKDM4EMAPTCA12CA1
Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 0.80 APP (0.74) APPKDM4EMAPTCA12CA1
Trans-4,4'-Dihydroxystilbene SCHEMBL145659 0.80 APP (0.74) APPKDM4EMAPTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698655-A REACTING AN ORGANOSILICON COMPOUND, AN OXYALKYLENE CONTAINING COMPOUND AND A CATALYST DOW CORNING CORPORATION (US) 1997-12-16 US claimed
US-5625023-A REACTION PRODUCT OF ORGANOSILICON COMPOUND, OXYALKYLENE COMPOUND, CATALYST DOW CORNING CORPORATION (US) 1997-04-29 US claimed
US-6805914-B2 COMPRISING A SOLVENTLESS SILICONE COATING COMPOSITION AND A LIQUID SILICONE MIST SUPPRESSANT COMPOSITION OBTAINED BY A METHOD COMPRISING REACTING A LARGE EXCESS OF AT LEAST ONE ORGANOHYDROGENSILICON COMPOUND CONTAINING AT LEAST THREE DOW CORNING CORPORATION 2004-10-19 US disclosed
EP-1294819-B1 SILICONE COATING CONTAINING SILICONE MIST SUPPRESSANT COMPOSITIONS DOW CORNING (US) 2004-10-06 EP disclosed
US-20030120000-A1 Silicone coatings containing silicone mist suppressant compositions DOW SILICONES CORPORATION 2003-06-26 US disclosed
EP-1294819-A2 SILICONE COATING CONTAINING SILICONE MIST SUPPRESSANT COMPOSITIONS Dow Corning Corporation (US) 2003-03-26 EP disclosed
US-6489407-B1 SOLVENT-FREE (CO-)POLYSILOXANES USED AS ANTISTICK AGENTS FOR LAMINATION OF PAPER SUBSTRATES DOW CORNING CORPORATION 2002-12-03 US disclosed
WO-2001098418-A2 SILICONE COATINGS CONTAINING SILICONE MIST SUPPRESSANT COMPOSITIONS DOW CORNING CORPORATION (US) 2001-12-27 WO disclosed
US-5994454-A REACTING AN ORGANOSILICON COMPOUND, AN OXYALKYLENE CONTAINING COMPOUND, AND A CATALYST. THE COMPOSITION, WHEN ADDED TO CURABLE SILICONE COATINGS, REDUCES THE AMOUNT OF SILICONE MIST IN HIGH SPEED COATING PROCESSES. DOW CORNING CORPORATION (US) 1999-11-30 US disclosed
EP-0716115-B1 Aerosol suppressant compositions for silicone coatings DOW CORNING (US) 1999-06-02 EP disclosed
US-5698655-A REACTING AN ORGANOSILICON COMPOUND, AN OXYALKYLENE CONTAINING COMPOUND AND A CATALYST DOW CORNING CORPORATION (US) 1997-12-16 US disclosed
US-5625023-A REACTION PRODUCT OF ORGANOSILICON COMPOUND, OXYALKYLENE COMPOUND, CATALYST DOW CORNING CORPORATION (US) 1997-04-29 US disclosed
EP-0542484-B1 Organosilicon compounds and compositions containing them DOW CORNING (GB) 1997-01-02 EP disclosed
EP-0716115-A2 Aerosol suppressant compositions for silicone coatings DOW CORNING CORPORATION (US) 1996-06-12 EP disclosed
US-5331020-A Organosilicon compounds and compositions containing them DOW CORNING LIMITED (GB) 1994-07-19 US disclosed
US-5270423-A Organosilicon compounds and compositions containing them DOW CORNING LIMITED (GB) 1993-12-14 US disclosed
EP-0542484-A1 Organosilicon compounds and compositions containing them Dow Corning Limited (GB) 1993-05-19 EP disclosed