Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120676 | 0.82 | — | — | |
| SCHEMBL7120183 | 0.80 | — | — | |
| SCHEMBL6428332 | 0.79 | GSK3B (0.42) | BRD4 | |
| SCHEMBL14912611 | 0.78 | NLRP3 (0.35) | BRD4ALDH1A1LMNA | |
| SCHEMBL6431430 | 0.77 | NAMPT (0.48) | RPS6KA3 | |
| SCHEMBL6782563 | 0.74 | — | — | |
| SCHEMBL13270258 | 0.73 | RPS6KA3 (0.52) | RPS6KA3LMNA | |
| SCHEMBL1841985 | 0.72 | KDM4E (0.44) | BRD4ALDH1A1LMNA | |
| SCHEMBL12929062 | 0.71 | L3MBTL1 (0.41) | BRD4ALDH1A1LMNA | |
| SCHEMBL29129120 | 0.70 | ADORA3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430028-A2 | AROMATIC AND HETEROAROMATIC ACID HALIDES FOR SYNTHESIZING POLYAMIDES | Pharmacia Corporation (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003018552-A2 | AROMATIC AND HETEROAROMATIC ACID HALIDES FOR SYNTHESIZING POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-06 | — | — | WO | disclosed |