SCHEMBL690149

SCHEMBL690149

OCc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.61
ESR2 Q92731 4/20 0.61
CA2 P00918 2/20 0.52
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
MKNK1 Q9BUB5 1/20 0.48
MKNK2 Q9HBH9 1/20 0.48
ABAT P80404 1/20 0.48
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TSHR P16473 1/20 0.46
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.44
CA12 O43570 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Parahydroxybenzyl Alcohol SCHEMBL28122520 1.00 ESR1 (0.61) ESR1ESR2CA2MMP3BCL2L1
SCHEMBL12092808 1.00 ESR1 (0.61) ESR1ESR2CA2MMP3BCL2L1
Parahydroxybenzyl Alcohol SCHEMBL62690 0.91
Parahydroxybenzyl Alcohol SCHEMBL10792062 0.88 ESR1 (0.58) ESR1ESR2CA2ABATMEN1
Parahydroxybenzyl Alcohol SCHEMBL27929616 0.88 ESR1 (0.58) ESR1ESR2CA2ABATMEN1
Parahydroxybenzyl Alcohol SCHEMBL27913908 0.88 ESR1 (0.58) ESR1ESR2CA2ABATMEN1
Parahydroxybenzyl Alcohol SCHEMBL27834691 0.88 ESR1 (0.58) ESR1ESR2CA2ABATMEN1
SCHEMBL11310791 0.88 MKNK1 (0.56) CA2MKNK1MKNK2TSHRHDAC2
SCHEMBL679970 0.88 MKNK1 (0.56) CA2MKNK1MKNK2TSHRHDAC2
SCHEMBL14173666 0.87 ESR1 (0.46) ESR1ESR2CA2MMP3BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341503-B1 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-02-13 EP claimed
US-6835212-B2 Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme WELLA AKTIENGESELLSCHAFT (DE) 2004-12-28 US claimed
EP-1341503-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2003-09-10 EP claimed
US-20030041391-A1 Agent and method for dyeing keratin fibres Wella GmbH (DE) 2003-03-06 US claimed
WO-2002047633-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-06-20 WO claimed
CN-116804027-A Benzoxazine type phthalonitrile monomer containing siloxane chain segment and preparation method thereof 江苏君澄空间科技有限公司 2023-09-26 CN disclosed
EP-4239000-A1 COMPOSITION FOR FORMING LOW DIELECTRIC CONSTANT RESIN, LOW DIELECTRIC MEMBER, AND ELECTRONIC DEVICE USING SAME JNC Corporation (JP) 2023-09-06 EP disclosed
CN-109988213-B Compound for polypeptide liquid phase synthesis carrier and preparation method and application thereof 深圳翰宇药业股份有限公司 2021-09-17 CN disclosed
US-10428032-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2019-10-01 US disclosed
WO-2017079867-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-05-18 WO disclosed
CN-103201306-B The condensation product that amino functional polymers is constituted SIKA技术股份公司 2016-11-02 CN disclosed
US-8304035-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
EP-1317413-A1 SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Les Laboratoires Servier (FR) 2003-06-11 EP disclosed
US-20030092637-A1 Novel compounds XYLOGEN AB (SE) 2003-05-15 US disclosed
US-20030041391-A1 Agent and method for dyeing keratin fibres Wella GmbH (DE) 2003-03-06 US disclosed
EP-1280773-A1 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES Wella Aktiengesellschaft (DE) 2003-02-05 EP disclosed
WO-2002085854-A1 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
WO-2002047633-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-06-20 WO disclosed
WO-2002022555-A1 SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2002-03-21 WO disclosed
WO-1995029155-A1 NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY PHARMACIA AB (SE) 1995-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092637-A1 Novel compounds ENTPD5, G6PD, G6PC1 ESR1 4428/4885ESR2 3677/4885CA2 2557/4885
US-10428032-B2 Polymerizable compound and optically anisotropic body CCNY, F12, CCNI ESR1 2664/4885ESR2 4195/4885CA2 4587/4885
US-20030041391-A1 Agent and method for dyeing keratin fibres KRT18, AKR7A2, ADH5 ESR1 4506/4885ESR2 3868/4885CA2 1930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.