Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 10/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608361 | 1.00 | DCK (0.44) | DCKALBPOLGBACE1ALDH1A1 | |
| SCHEMBL12995147 | 0.86 | ALDH1A1 (0.35) | DCKBACE1ALDH1A1HTT | |
| SCHEMBL12995146 | 0.86 | ALDH1A1 (0.35) | DCKBACE1ALDH1A1HTT | |
| SCHEMBL13881298 | 0.85 | POLB (0.38) | DCKALDH1A1HTT | |
| SCHEMBL3621139 | 0.85 | POLB (0.38) | DCKALDH1A1HTT | |
| SCHEMBL3654823 | 0.85 | POLB (0.38) | DCKALDH1A1HTT | |
| SCHEMBL16639153 | 0.85 | POLB (0.38) | DCKALDH1A1HTT | |
| SCHEMBL3621141 | 0.85 | POLB (0.38) | DCKALDH1A1HTT | |
| SCHEMBL13881514 | 0.84 | LMNA (0.43) | ALBPOLGALDH1A1 | |
| SCHEMBL13881282 | 0.84 | LMNA (0.43) | ALBPOLGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587480-A | TREATING HIV AND HEPATITIS VIRUS INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 1996-12-24 | — | — | US | claimed |
| EP-1473294-A2 | Substituted 1,3-oxathiolanes with antiviral properties | Shire Biochem Inc. (CA) | 2004-11-03 | — | — | EP | disclosed |
| EP-1153924-B1 | Substituted 1,3-oxathiolanes with antiviral properties | SHIRE BIOCHEM INC (CA) | 2004-09-01 | — | — | EP | disclosed |
| US-6369066-B1 | HIV INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 2002-04-09 | — | — | US | disclosed |
| EP-0756595-B1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | SHIRE BIOCHEM INC (CA) | 2002-03-06 | — | — | EP | disclosed |
| EP-1153924-A2 | Substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC (CA) | 2001-11-14 | — | — | EP | disclosed |
| US-5587480-A | TREATING HIV AND HEPATITIS VIRUS INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 1996-12-24 | — | — | US | disclosed |