Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 4/20 | 0.32 |
| ▸ | NPY1R | P25929 | 2/20 | 0.32 |
| ▸ | NPY4R | P50391 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528025 | 0.97 | NPY4R (0.34) | KMT2AMEN1POLBL3MBTL1ADRB3 | |
| SCHEMBL6901717 | 0.92 | EPOR (0.35) | EPORNPY1RNPY4RNPY5RALDH1A1 | |
| SCHEMBL7043493 | 0.91 | MEN1 (0.35) | KMT2AMEN1POLBL3MBTL1EPOR | |
| SCHEMBL6900020 | 0.91 | CASR (0.38) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7036782 | 0.85 | EPOR (0.36) | KMT2AMEN1EPORNPY1RNPY4R | |
| SCHEMBL6898240 | 0.85 | NPY1R (0.38) | NPY1RNPY4RNPY5R | |
| SCHEMBL6898666 | 0.84 | CYP2C9 (0.45) | KMT2AMEN1POLBNPY1RNPY4R | |
| SCHEMBL6898966 | 0.84 | TDP1 (0.36) | KMT2ANPY1RNPY4RNPY5RLMNA | |
| SCHEMBL7059809 | 0.84 | NPY1R (0.42) | KMT2AMEN1POLBNPY1RNPY4R | |
| SCHEMBL6899868 | 0.84 | NPY1R (0.42) | KMT2AMEN1POLBNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |