Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904772 | 0.96 | HSD11B1 (0.32) | HSD11B1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6898054 | 0.92 | — | — | |
| SCHEMBL6902721 | 0.89 | HSD11B1 (0.37) | RARBHSD17B10TSHRHSD11B1ALDH1A1 | |
| SCHEMBL6903737 | 0.89 | PTGS1 (0.35) | RARBHSD17B10TSHRHSD11B1ALDH1A1 | |
| SCHEMBL6902288 | 0.88 | EDNRB (0.31) | — | |
| Hydrochloric Acid SCHEMBL6898160 | 0.85 | RARB (0.33) | RARBHSD17B10TSHRHSD11B1TOP2A | |
| SCHEMBL6903352 | 0.85 | CHRM2 (0.33) | ALDH1A1MAPTS1PR1CHRM2CHRM5 | |
| SCHEMBL6901827 | 0.85 | CHRM2 (0.35) | ALDH1A1MAPTS1PR1CHRM2CHRM5 | |
| SCHEMBL6902351 | 0.85 | EIF4A1 (0.38) | HSD11B1 | |
| SCHEMBL6902435 | 0.83 | TDP1 (0.36) | HSD17B10TSHRALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |