Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898578 | 0.91 | ALDH1A1 (0.37) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL6903706 | 0.89 | ALDH1A1 (0.31) | TDP1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6902288 | 0.89 | EDNRB (0.31) | — | |
| SCHEMBL6903036 | 0.88 | GSK3B (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6901142 | 0.88 | S1PR1 (0.33) | ALDH1A1NPC1RAB9A | |
| SCHEMBL6904337 | 0.88 | NPC1 (0.35) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL6898054 | 0.86 | — | — | |
| SCHEMBL6903696 | 0.86 | CHRM2 (0.33) | KDM4EALDH1A1HPGDMAPTCHRM2 | |
| SCHEMBL6902063 | 0.85 | ALDH1A1 (0.34) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL6904772 | 0.84 | HSD11B1 (0.32) | ALDH1A1MEN1MAPTALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |