Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902446 | 0.92 | NPY2R (0.47) | MAPTGAAKDM4ECYP3A4CYP2C9 | |
| SCHEMBL6901950 | 0.90 | MCHR1 (0.44) | MAPTKDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7050368 | 0.90 | MAPT (0.42) | MAPTGAAKDM4ECYP3A4CYP2C9 | |
| SCHEMBL6901971 | 0.89 | MAPT (0.41) | MAPTGAAKDM4ECYP3A4CYP2C9 | |
| SCHEMBL6052241 | 0.88 | MAPT (0.45) | MAPTKDM4ECYP3A4CYP2C9CYP2C19 | |
| Water SCHEMBL6052346 | 0.87 | MAPT (0.44) | MAPTKDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6901167 | 0.84 | MCHR1 (0.44) | MAPTKDM4EMCHR1ACP1 | |
| SCHEMBL6897156 | 0.83 | MAPT (0.46) | MAPTKDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7057946 | 0.83 | ALDH1A1 (0.40) | MAPTGAAKDM4EMCHR1FGFR1 | |
| SCHEMBL7060964 | 0.82 | ALDH1A1 (0.44) | MAPTGAAKDM4EMCHR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |