Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.66 |
| ▸ | MGAM | O43451 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | SI | P14410 | 4/20 | 0.66 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.66 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000252 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL28851907 | 0.83 | KDM4E (0.70) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL10163324 | 0.80 | KDM4E (0.68) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL23918236 | 0.79 | KDM4E (0.66) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL11340093 | 0.79 | MGAM (1.00) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL474273 | 0.79 | KDM4E (0.66) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL1143313 | 0.79 | KDM4E (0.66) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL6538646 | 0.79 | KDM4E (0.66) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL1143676 | 0.79 | KDM4E (1.00) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM | |
| SCHEMBL17725821 | 0.79 | KDM4E (0.66) | ALDH1A1SMN1; SMN2LMNAKDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101284820-B | Amino peptidase inhibiting substance and synthetic method | UNIV NANCHANG | 2011-05-04 | — | — | CN | claimed |
| CN-101284820-A | Amino peptidase inhibiting substance and synthetic method | UNIV NANCHANG (CN) | 2008-10-15 | — | — | CN | claimed |
| CN-119661470-A | Thiadiazole urea compound or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-03-21 | — | — | CN | disclosed |
| US-12187729-B2 | Compounds having PDE9A inhibitory activity, and pharmaceutical uses thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2025-01-07 | — | — | US | disclosed |
| EP-3892622-B1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | KOREA RES INST CHEMICAL TECH (KR) | 2024-07-24 | — | — | EP | disclosed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | disclosed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | disclosed |
| CN-113166159-B | Compounds having PDE9A inhibiting activity and pharmaceutical uses thereof | 韩国化学研究院 | 2023-10-24 | — | — | CN | disclosed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | disclosed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | disclosed |
| CN-112279845-B | Aryl or heteroaryl substituted thiadiazoles compounds and antibacterial application thereof | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |
| US-7867980-B2 | Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 2010-07-22 | — | — | US | disclosed |
| CN-101284820-A | Amino peptidase inhibiting substance and synthetic method | UNIV NANCHANG (CN) | 2008-10-15 | — | — | CN | disclosed |
| EP-0159707-B1 | TRIAZOLOPYRIMIDINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-4652646-A | ANTIALLERGENS | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0159707-A2 | Triazolopyrimidine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |
| EP-0005783-B1 | IMIDAZO (2.1-B)-(1.3.4)-THIADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |
| US-4265898-A | ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| EP-0005783-A1 | Imidazo (2.1-b)-(1.3.4)-thiadiazoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187729-B2 | Compounds having PDE9A inhibitory activity, and pharmaceutical uses thereof | PDE9A, PDE5A, PDE3A | ALDH1A1 517/4885SMN1; SMN2 944/4885LMNA 1466/4885 |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | ALDH1A1 575/4885SMN1; SMN2 4692/4885LMNA 4359/4885 |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | ALDH1A1 468/4885SMN1; SMN2 4606/4885LMNA 4601/4885 |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | SIRT6, LAS1L, MRPS18A | ALDH1A1 3217/4885SMN1; SMN2 1070/4885LMNA 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.