SCHEMBL6902256

SCHEMBL6902256

NN=Cc1ccc(-c2ccc(OC[C@@H]3C[C@@H](CC(=O)O)C(=O)N3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.68
ITGA2B P08514 2/20 0.68
PPARD Q03181 11/20 0.37
PPARA Q07869 5/20 0.37
PPARG P37231 5/20 0.37
FFAR1 O14842 3/20 0.37
FFAR4 Q5NUL3 2/20 0.34
POLB P06746 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MMP2 P08253 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7283786 0.83 ITGB3 (0.73) ITGB3ITGA2BPPARDPPARAPPARG
SCHEMBL7284201 0.81 ITGB3 (0.71) ITGB3ITGA2BPPARDPPARAPPARG
SCHEMBL7283166 0.81 ITGB3 (0.71) ITGB3ITGA2BPPARDPPARAPPARG
SCHEMBL7273790 0.81 ITGB3 (0.70) ITGB3ITGA2BPPARDPPARAPPARG
Fradafiban SCHEMBL8863359 0.81 ITGB3 (1.00) ITGB3ITGA2B
Fradafiban SCHEMBL380350 0.81 ITGB3 (1.00) ITGB3ITGA2B
Fradafiban SCHEMBL7280818 0.80 ITGB3 (0.98) ITGB3ITGA2B
SCHEMBL7276743 0.78 ITGB3 (0.76) ITGB3ITGA2BPPARDPPARAPPARG
SCHEMBL7277088 0.78 ITGB3 (0.78) ITGB3ITGA2BPPARDPPARAPPARG
SCHEMBL7273484 0.77 ITGB3 (0.77) ITGB3ITGA2BPPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891774-B1 Sustained release microcapsule for water soluble drug TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2004-06-16 EP disclosed
US-20020037837-A1 Process for producing sustained-release preparation TAKADA SHIGEYUKI (JP) 2002-03-28 US disclosed
US-6287587-B2 Forming a water in oil emulsion comprising a solution containing a water-soluble 2-piprazinone-1-acetic acid derivative and arganine as intergrin antagonist, a solvent, abiodegradable polymer, and fat and oil, removing the solvent TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-09-11 US disclosed
US-20010018075-A1 Process for producing sustained-release preparation SHIGEYUKI TAKADA (JP) 2001-08-30 US disclosed
EP-0891774-A2 Process for producing sustained release preparation Takeda Chemical Industries, Ltd. (JP) 1999-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037837-A1 Process for producing sustained-release preparation LIPA, LIPE, TTPA ITGB3 4218/4885ITGA2B 3765/4885PPARD 792/4885
US-20010018075-A1 Process for producing sustained-release preparation LIPA, LIPE, TTPA ITGB3 4218/4885ITGA2B 3765/4885PPARD 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.