SCHEMBL6902432

SCHEMBL6902432

COC(=O)c1ccc(NS(C)(=O)=O)cc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 2/20 0.61
GAA P10253 1/20 0.53
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 1/20 0.39
MAPK10 P53779 1/20 0.39
TP53 P04637 1/20 0.39
GLA P06280 1/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306857 0.92 CDK1 (0.61) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL10396053 0.88 CDK1 (0.62) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL8782215 0.88 CDK1 (0.62) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL5846414 0.88 CDK1 (0.62) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL5847785 0.88 CDK1 (0.61) CDK1GAACYP1A2MAPTHPGD
SCHEMBL5847781 0.88 CDK1 (0.61) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL8536414 0.87 CDK1 (0.80) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL11385667 0.85 CDK1 (0.57) CDK1GAACYP1A2MAPTTP53
SCHEMBL8507050 0.84 CDK1 (0.56) CDK1GAAMEN1KMT2ACYP1A2
SCHEMBL10395502 0.84 CDK1 (0.56) CDK1GAAMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116600643-A Herbicide mixture, herbicide composition, method for controlling undesired vegetation and kit 安道麦阿甘有限公司 2023-08-15 CN disclosed
CN-111807997-B Synthesis method of N- (4-methoxycarbonyl-3-aminosulfonylbenzyl) methanesulfonamide 南京合创药业有限公司 2022-09-23 CN disclosed
CN-113999178-A Method for preparing mesosulfuron-methyl by one-pot method 江苏省农用激素工程技术研究中心有限公司 2022-02-01 CN disclosed
CN-113999179-A Method for synthesizing mesosulfuron-methyl by one-pot method 江苏省农用激素工程技术研究中心有限公司 2022-02-01 CN disclosed
CN-111807997-A Synthesis method of N- (4-methoxycarbonyl-3-aminosulfonylbenzyl) methanesulfonamide 南京合创药业有限公司 2020-10-23 CN disclosed
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-09-02 US disclosed
US-6723681-B2 HERBICIDE COMBINATIONS WITH AN EFFECTIVE CONTENT OF BROAD-SPECTRUM HERBICIDES FROM THE GROUP GLUFOSINATE (SALTS) AND RELATED COMPOUNDS, GLYPHOSATE (SALTS) AND RELATED COMPOUNDS, IMIDAZOLINONES, HERBICIDAL AZOLES HOECHST SCHERING AGREVO GMBH (DE) 2004-04-20 US disclosed
US-20030022792-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT CEREAL CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-01-30 US disclosed
US-20030004064-A1 Synergistic active compound combinations for controlling harmful plants AVENTIS CROPSCIENCE GMBH (DE) 2003-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030004064-A1 Synergistic active compound combinations for controlling harmful plants DDT, AADAT, MTX1 CDK1 487/4885GAA 1094/4885MEN1 3955/4885
US-20030022792-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT CEREAL CROPS PPOX, PNPO, PAOX CDK1 1233/4885GAA 1035/4885MEN1 3494/4885
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants L3MBTL4, TTL, EBPL CDK1 2025/4885GAA 4417/4885MEN1 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.