Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905043 | 0.88 | ALDH1A1 (0.36) | ALDH1A1HPGDHSD17B10SMN1; SMN2CYP1A2 | |
| SCHEMBL6903159 | 0.86 | ABCB1 (0.32) | ALDH1A1HPGDHSD17B10SMN1; SMN2CYP1A2 | |
| SCHEMBL6898578 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HPGDHSD17B10SMN1; SMN2TSHR | |
| SCHEMBL6902435 | 0.85 | TDP1 (0.36) | ALDH1A1HPGDHSD17B10SMN1; SMN2TSHR | |
| SCHEMBL6903255 | 0.84 | ABCB1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6902667 | 0.83 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10SMN1; SMN2CYP1A2 | |
| SCHEMBL6903036 | 0.83 | GSK3B (0.33) | GSK3B | |
| SCHEMBL6902681 | 0.83 | MAOA (0.33) | ALDH1A1HPGDHSD17B10SMN1; SMN2TSHR | |
| SCHEMBL6902288 | 0.82 | EDNRB (0.31) | — | |
| SCHEMBL6903706 | 0.82 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |