Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.39 |
| ▸ | RELA | Q04206 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902056 | 0.96 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6902576 | 0.94 | SMN1; SMN2 (0.33) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6901825 | 0.91 | ALDH1A1 (0.34) | RAB9ANPC1SMN1; SMN2BRS3MAPT | |
| SCHEMBL6902522 | 0.87 | CCR1 (0.37) | RAB9ANPC1SMN1; SMN2TP53STAT3 | |
| SCHEMBL6902437 | 0.86 | BRS3 (0.38) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL6902605 | 0.85 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6903898 | 0.84 | CYP3A4 (0.37) | RAB9ANPC1SMN1; SMN2TP53STAT3 | |
| SCHEMBL6897160 | 0.82 | CCR1 (0.33) | — | |
| SCHEMBL6902617 | 0.82 | ALOX5AP (0.30) | — | |
| SCHEMBL6904267 | 0.82 | CYP1A2 (0.36) | RAB9ANPC1SMN1; SMN2BRS3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |