Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902522 | 0.94 | CCR1 (0.37) | CYP3A4CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL6897160 | 0.89 | CCR1 (0.33) | CYP3A4CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL6901825 | 0.89 | ALDH1A1 (0.34) | CYP3A4CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL6902299 | 0.88 | CCR1 (0.32) | CYP3A4CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL6902565 | 0.88 | CCR1 (0.32) | CYP3A4CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL6902359 | 0.87 | CYP3A4 (0.36) | CYP3A4CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL6902576 | 0.86 | SMN1; SMN2 (0.33) | CCR1CCR5CCR8HDAC6NPC1 | |
| SCHEMBL6899180 | 0.85 | KDM4E (0.35) | CCR1CCR5CCR8HDAC6NPC1 | |
| SCHEMBL6902650 | 0.84 | RAB9A (0.39) | NPC1RAB9ATP53STAT3SMN1; SMN2 | |
| SCHEMBL6902617 | 0.84 | ALOX5AP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |