SCHEMBL690304

SCHEMBL690304

CS(=O)(=O)C(N)c1ccccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
ALOX15 P16050 2/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAPT P10636 3/20 0.42
HDAC8 Q9BY41 1/20 0.42
F2 P00734 3/20 0.40
PRSS1 P07477 3/20 0.40
PRSS2 P07478 3/20 0.40
PRSS3 P35030 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
MYC P01106 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3648818 0.80 ALOX15 (0.44) ALDH1A1ALOX15MAPTHDAC8F2
SCHEMBL1449566 0.77 ALDH1A1 (0.52) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL6372852 0.77 ALDH1A1 (0.56) ALDH1A1ALOX15GAAKMT2ATDP1
Hydrochloric Acid SCHEMBL6093184 0.76 ALDH1A1 (0.50) ALDH1A1ALOX15GAAKMT2ATDP1
Hydrazine SCHEMBL27571459 0.75 ALDH1A1 (0.54) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL254364 0.74 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
Hydrogen Peroxide SCHEMBL9514730 0.74 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL134091 0.74 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL29657201 0.74 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
Benzene SCHEMBL28132022 0.74 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230136215-A1 PRODUCTION OF DUNALIELLA UNIVERSITY OF GREENWICH (GB) 2023-05-04 US disclosed
US-20200368302-A1 PRODUCTION OF DUNALIELLA UNIVERSITY OF GREENWICH (GB) 2020-11-26 US disclosed
EP-2928869-A1 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2015-10-14 EP disclosed
WO-2014086865-A1 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2014-06-12 WO disclosed
EP-2421533-A1 NOVEL ANTI-INFLAMMATORY AGENTS RESVERLOGIX CORP. (CA) 2012-02-29 EP disclosed
WO-2010123975-A1 NOVEL ANTI-INFLAMMATORY AGENTS RESVERLOGIX CORP. (CA) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230136215-A1 PRODUCTION OF DUNALIELLA DDT, DLD, DAGLA ALDH1A1 2223/4885ALOX15 1214/4885GAA 1167/4885
US-20200368302-A1 PRODUCTION OF DUNALIELLA DDT, DLD, DAGLA ALDH1A1 2223/4885ALOX15 1214/4885GAA 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.