SCHEMBL6903159

SCHEMBL6903159

CCc1ccc(C2=Cc3c(-c4ccc5ccccc5c4)cccc3C2[Zr]C2C(c3ccc(CC)o3)=Cc3c(-c4ccc5ccccc5c4)cccc32)o1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.32
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GSTP1 P09211 1/20 0.30
S1PR4 O95977 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903255 0.92 ABCB1 (0.31) ABCB1
SCHEMBL6902545 0.87 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6902063 0.86 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP3A4CYP2C9HPGD
SCHEMBL6895504 0.86 CHRM2 (0.34) ALOX5PTGS1PTGS2CHRM2CHRM4
SCHEMBL6903696 0.85 CHRM2 (0.33) ALOX5PTGS1PTGS2CHRM2CHRM4
SCHEMBL6905043 0.85 ALDH1A1 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL6903875 0.84 ABCB1 (0.32) ABCB1ALOX5PTGS1PTGS2CHRM2
SCHEMBL6903190 0.84 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6903109 0.84 HTR6 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6905004 0.83 CHRM2 (0.32) ALOX5PTGS1PTGS2CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033371-B1 Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2004-01-28 EP claimed