Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899180 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6895367 | 0.83 | TGFBR1 (0.38) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6901138 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6902284 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6903610 | 0.79 | PKM (0.40) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6903067 | 0.77 | NPC1 (0.34) | KDM4EMAPTSMN1; SMN2NPC1HTR2C | |
| SCHEMBL6901820 | 0.77 | PKM (0.32) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7592887 | 0.77 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6902406 | 0.76 | TGFBR1 (0.39) | MAPTTP53NPC1TGFBR1GAA | |
| SCHEMBL6900002 | 0.76 | TRPV1 (0.39) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |