Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18261221 | 0.82 | METAP1 (0.46) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27845467 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5684541 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25878365 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28265785 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8917219 | 0.76 | METAP1 (0.41) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28112705 | 0.76 | METAP1 (0.41) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8428997 | 0.76 | METAP1 (0.41) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3273192 | 0.76 | METAP1 (0.41) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL601330 | 0.75 | MAPT (0.45) | METAP1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268575-B1 | NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2004-06-09 | — | — | EP | disclosed |
| CN-1133660-C | High temp olefin polymerization process | ����ɭ���ڻ�ѧר����˾ | 2004-01-07 | — | — | CN | disclosed |
| US-20030083515-A1 | Nitrogen-containing group-13 anionic compounds for olefin polymerization | RODRIGUEZ GEORGE (US) | 2003-05-01 | — | — | US | disclosed |
| EP-1268575-A2 | NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001081435-A2 | NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
| CN-1291999-A | High temperature polymerization of olefins | EXXON CHEMICAL PATENTS INC (US) | 2001-04-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083515-A1 | Nitrogen-containing group-13 anionic compounds for olefin polymerization | SFN, SLC7A5, NOTUM | METAP1 2537/4885MAPT 2633/4885MEN1 1604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.