Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723267 | 0.91 | NLRP3 (0.43) | NLRP3MMP8SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2836423 | 0.89 | KMT2A (0.50) | NLRP3MMP8SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27546738 | 0.86 | ALDH1A1 (0.40) | NLRP3MMP8SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13572972 | 0.82 | KMT2A (0.47) | NLRP3SMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL23944802 | 0.81 | MMP8 (0.42) | NLRP3MMP8SMN1; SMN2KMT2ACA12 | |
| SCHEMBL1477896 | 0.81 | MAPT (0.39) | MMP8KDM4EALDH1A1KMT2ACA12 | |
| SCHEMBL5251229 | 0.81 | KMT2A (0.50) | NLRP3MMP8SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8323986 | 0.81 | MMP8 (0.44) | NLRP3MMP8SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2836425 | 0.81 | KMT2A (0.47) | NLRP3MMP8SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13869970 | 0.81 | MMP8 (0.49) | NLRP3MMP8ALDH1A1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1197841-C | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2005-04-20 | — | — | CN | disclosed |
| EP-1002788-B1 | Process for preparing halogenated phenylmalonates | BASF AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| US-6156925-A | Process for the preparation of halogenated phenylmaloates | AMERICAN CYANAMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| EP-1002788-A1 | Process for preparing halogenated phenylmalonates | American Cyanamid Company (US) | 2000-05-24 | — | — | EP | disclosed |
| CN-1250044-A | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2000-04-12 | — | — | CN | disclosed |