Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6662100 | 0.85 | HTR6 (0.37) | HTR6 | |
| SCHEMBL13462187 | 0.82 | CHRNB2 (0.43) | HTR6SMN1; SMN2HRH3 | |
| SCHEMBL21039950 | 0.82 | CHRNB2 (0.43) | HTR6SMN1; SMN2HRH3 | |
| SCHEMBL28356121 | 0.80 | HTR6 (0.43) | HTR6HSD17B10HRH3 | |
| SCHEMBL31660918 | 0.75 | USP2 (0.40) | HTR6MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20523597 | 0.75 | USP2 (0.40) | HTR6MAPTKMT2AMEN1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL20523513 | 0.74 | CHRNB2 (0.36) | HTR6 | |
| SCHEMBL24127421 | 0.71 | MAPT (0.44) | MAPTKMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL22608794 | 0.70 | HTR6 (0.39) | HTR6 | |
| SCHEMBL14826557 | 0.70 | DPP4 (0.40) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004517873-A | — | — | 2004-06-17 | — | — | JP | claimed |
| EP-1368343-A1 | 1-(2-METHOXYBENZYL)-3-BENZHYDRYLPIPERAZINES AS TACHYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-10 | — | — | EP | claimed |
| WO-2002055518-A1 | 1-(2-METHOXYBENZYL)-3-BENZHYDRYLPIPERAZINES AS TACHYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-18 | — | — | WO | claimed |