Albizziine

Albizziine

SCHEMBL690347

NC(=O)NC[C@H](N)C(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFPT1 Q06210 1/20 0.48
ALOX15 P16050 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
KMT2A Q03164 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
BCAT2 O15382 1/20 0.44
GGT1 P19440 4/20 0.43
SLC7A5 Q01650 1/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GSR P00390 1/20 0.41
CYP1A2 P05177 1/20 0.41
GRIK1 P39086 1/20 0.41
GRM5 P41594 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Albizziine SCHEMBL9361011 1.00 GFPT1 (0.48) GFPT1ALOX15BLMPMP22KMT2A
Albizziine SCHEMBL439790 1.00 GFPT1 (0.48) GFPT1ALOX15BLMPMP22KMT2A
Albizziine SCHEMBL1006298 1.00 GFPT1 (0.48) GFPT1ALOX15BLMPMP22KMT2A
Albizziine SCHEMBL1006299 1.00 GFPT1 (0.48) GFPT1ALOX15BLMPMP22KMT2A
Albizziine SCHEMBL29791573 0.98 GFPT1 (0.47) GFPT1ALOX15BLMPMP22KMT2A
SCHEMBL31524073 0.82 CYP2D6 (0.50) GFPT1PTGS1SLC7A11GGT1SLC7A5
SCHEMBL1527344 0.81 GFPT1 (0.46) GFPT1ALOX15BLMPMP22KMT2A
SCHEMBL574087 0.81 GFPT1 (0.46) GFPT1ALOX15BLMPMP22KMT2A
SCHEMBL393844 0.81 GFPT1 (0.46) GFPT1ALOX15BLMPMP22KMT2A
SCHEMBL1512859 0.81 SLC7A5 (0.43) ALOX15BLMPMP22KMT2APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 US claimed
EP-4359377-A1 BIVALENT COMPOUNDS, CONJUGATES AND USES THEREOF Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-05-01 EP claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 CN claimed
US-20230399661-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2023-12-14 US claimed
US-20230383291-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2023-11-30 US claimed
EP-4232590-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS Feldan Bio Inc. (CA) 2023-08-30 EP claimed
EP-4229207-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION Feldan Bio Inc. (CA) 2023-08-23 EP claimed
CN-116615205-A Peptide-based transduction of non-anionic polynucleotide analogs for modulation of gene expression 费尔丹生物公司 2023-08-18 CN claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 CN claimed
US-20230019098-A1 BIVALENT COMPOUNDS, CONJUGATES AND USES THEREOF RISEN (SHANGHAI) MEDICINAL TECH CO., LTD. (CN) 2023-01-19 US claimed
EP-0910655-A4 VACCINES FOR TREATMENT OF LYMPHOMA AND LEUKEMIA GENITOPE CORP (US) 2006-05-03 EP claimed
US-20040096452-A1 Vaccines for treatment of lymphoma and leukemia DENNEY DAN W (US) 2004-05-20 US claimed
US-20020160006-A1 Methods of treating lymphoma and leukemia DENNEY DAN W (US) 2002-10-31 US claimed
US-6191168-B1 BACTERICIDES Rubenstein, Edward 2001-02-20 US claimed
US-5972334-A IMPROVED METHODS FOR THE AMPLIFICATION AND EXPRESSION OF RECOMBINANT GENES IN CELLS. THE AMPLIFIED CELLS PROVIDE LARGE QUANTITIES OF RECOMBINANT PROTEINS SUITABLE FOR IMMUNOTHERAPY FOR TREATMENT OF LYMPHOMAS AND LEUKEMIAS. GENITOPE CORPORATION 1999-10-26 US claimed
EP-0910655-A1 VACCINES FOR TREATMENT OF LYMPHOMA AND LEUKEMIA Genitope Corporation (US) 1999-04-28 EP claimed
US-5776746-A EFFICIENT ISOLATION OF AMPLIFIED CELL LINES WHICH EXPRESS THEPROTEINS OF INTEREST IN A RELATIVELY SHORT PERIOD OF TIME GENITOPE CORPORATION (US) 1998-07-07 US claimed
WO-1997041244-A1 VACCINES FOR TREATMENT OF LYMPHOMA AND LEUKEMIA GENITOPE CORPORATION (US) 1997-11-06 WO claimed
US-5011776-A Shuttle vector, utilizing the E. coli asparagine synthetase gene, and capable of dominant transfection and amplification in animal cells THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING (MCGILL UNIVERSITY) (CA) 1991-04-30 US claimed
EP-0319206-A2 Gene amplification BERLEX LABORATORIES, INC. (US) 1989-06-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY SCAMP2, SLC7A1, NUMA1 GFPT1 1712/4885ALOX15 4632/4885BLM 2300/4885
US-20230019098-A1 BIVALENT COMPOUNDS, CONJUGATES AND USES THEREOF PLK1, BRDT, BCR GFPT1 4407/4885ALOX15 3690/4885BLM 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.