SCHEMBL393844

SCHEMBL393844

N=C(N)NCC(N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFPT1 Q06210 1/20 0.46
ALOX15 P16050 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
KMT2A Q03164 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC7A11 Q9UPY5 1/20 0.41
GGT1 P19440 4/20 0.40
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
CASR P41180 1/20 0.38
SLC7A5 Q01650 1/20 0.38
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GSR P00390 1/20 0.38
CYP1A2 P05177 1/20 0.38
GRIK1 P39086 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527344 1.00 GFPT1 (0.46) GFPT1ALOX15BLMPMP22KMT2A
SCHEMBL574087 1.00 GFPT1 (0.46) GFPT1ALOX15BLMPMP22KMT2A
Hydrochloric Acid SCHEMBL503105 0.98 GFPT1 (0.44) GFPT1ALOX15BLMPMP22KMT2A
Hydrochloric Acid SCHEMBL17239121 0.98 GFPT1 (0.44) GFPT1ALOX15BLMPMP22KMT2A
Adipic Acid SCHEMBL8055763 0.89 BHMT (0.45) GFPT1ALOX15BLMPMP22KMT2A
SCHEMBL19371887 0.84 GFPT1 (0.32) GFPT1
SCHEMBL22122969 0.84 GFPT1 (0.32) GFPT1
SCHEMBL27644228 0.84 SLC7A5 (0.42) ALOX15BLMPMP22KMT2APTGS1
SCHEMBL27644223 0.84 SLC7A5 (0.42) ALOX15BLMPMP22KMT2APTGS1
SCHEMBL1478033 0.82 SLC7A5 (0.41) ALOX15BLMPMP22KMT2APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-20260091126-A1 AMINO ACID-MODIFIED LIPIDS FOR RNA DELIVERY UNIV MISSOURI (US) 2026-04-02 US claimed
US-12540161-B2 Linkers BICYCLETX LIMITED (GB) 2026-02-03 US claimed
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2026-01-29 US claimed
US-20250346589-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS UNIV ERASMUS MED CT ROTTERDAM (NL) 2025-11-13 US claimed
EP-4590670-A1 PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS Erasmus University Rotterdam Medical Center (NL) 2025-07-30 EP claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
EP-3833676-B1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2025-05-28 EP claimed
EP-4529474-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS Erasmus University Rotterdam Medical Center (NL) 2025-04-02 EP claimed
WO-2025063849-A2 DIMERIC FAP TARGETING AGENTS ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) 2025-03-27 WO claimed
EP-1986683-A2 COMPOSITIONS AND METHODS FOR EFFECTING CONTROLLED POSTERIOR VITREOUS DETACHMENT Bausch & Lomb Incorporated (US) 2008-11-05 EP claimed
WO-2008098151-A2 POLAR HYDROPHILIC PRODRUGS OF AMPHETAMINE AND OTHER STIMULANTS AND PROCESSES FOR MAKING AND USING THE SAME KEMPHARM, INC. (US) 2008-08-14 WO claimed
US-20070212358-A1 Compositions and Methods for Effecting Controlled Posterior Vitreous Detachment BAUSCH & LOMB INCORPORATED 2007-09-13 US claimed
WO-2007101005-A2 COMPOSITIONS AND METHODS FOR EFFECTING CONTROLLED POSTERIOR VITREOUS DETACHMENT BAUSCH & LOMB INCORPORATED (US) 2007-09-07 WO claimed
US-20070196350-A1 Compositions and Methods for Effecting Controlled Posterior Vitreous Detachment BAUSCH & LOMB INCORPORATED 2007-08-23 US claimed
EP-1189623-B1 METHOD AND COMPOSITION FOR INHIBITING CARDIOVASCULAR CELL PROLIFERATION UNIV LELAND STANFORD JUNIOR (US) 2007-03-14 EP claimed
US-20040074504-A1 Method and composition for inhibiting cardiovascular cell proliferation COOKE JOHN P (US) 2004-04-22 US claimed
US-6605115-B1 Method and composition for inhibiting cardiovascular cell proliferation BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-08-12 US claimed
EP-0561412-B1 Parathyroid hormone derivatives TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-02-03 EP claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM GFPT1 213/4885ALOX15 3961/4885BLM 3782/4885
US-20250346589-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS SSTR2, SSTR5, SSTR1 GFPT1 1207/4885ALOX15 4502/4885BLM 3001/4885
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES PHAX, TPX2, MLX GFPT1 1331/4885ALOX15 2769/4885BLM 541/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT GFPT1 1014/4885ALOX15 2512/4885BLM 4297/4885
US-20260091126-A1 AMINO ACID-MODIFIED LIPIDS FOR RNA DELIVERY METTL16, SLC7A1, RNMT GFPT1 743/4885ALOX15 792/4885BLM 3778/4885
US-12540161-B2 Linkers ADM2, CDA, DCTD GFPT1 2666/4885ALOX15 3617/4885BLM 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.