SCHEMBL690365

SCHEMBL690365

CCC[Si](OC)(OC)OCN1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.42
ALDH1A1 P00352 3/20 0.42
BLM P54132 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GMNN O75496 1/20 0.42
THPO P40225 1/20 0.42
PMP22 Q01453 1/20 0.42
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
WRN Q14191 1/20 0.41
HIF1A Q16665 1/20 0.41
FAAH O00519 5/20 0.39
PTGS1 P23219 3/20 0.39
PTGS2 P35354 3/20 0.39
GSK3A P49840 3/20 0.36
GSK3B P49841 3/20 0.36
HSP90AA1 P07900 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3963636 0.72 MGLL (0.46) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL296687 0.70 MGLL (0.56) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL6480093 0.70 MGLL (0.48) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL24854625 0.67 MGLL (0.44) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL277926 0.67 MGLL (0.55) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL2034096 0.67 LMNA (0.34) LMNA
SCHEMBL28989001 0.67
SCHEMBL8130395 0.66 LMNA (0.44) LMNA
SCHEMBL35169 0.66 LMNA (0.44) LMNA
SCHEMBL3961052 0.66 MGLL (0.48) MGLLALDH1A1BLMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140110101-A1 Well Tubular, Coating System and Method for Oilfield Applications SchlumbergerTechnology Corporation (US) 2014-04-24 US disclosed
EP-2422040-A2 WELL TUBULAR, COATING SYSTEM AND METHOD FOR OILFIELD APPLICATIONS Services Pétroliers Schlumberger (FR) 2012-02-29 EP disclosed
WO-2010122519-A2 WELL TUBULAR, COATING SYSTEM AND METHOD FOR OILFIELD APPLICATIONS SCHLUMBERGER CANADA LIMITED (CA) 2010-10-28 WO disclosed
US-20090200013-A1 WELL TUBULAR, COATING SYSTEM AND METHOD FOR OILFIELD APPLICATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2009-08-13 US disclosed