Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Threonine SCHEMBL7805411 | 0.90 | GAA (0.41) | GAAMAPTKDM4ETDP1NPC1 | |
| Benzene SCHEMBL27623238 | 0.85 | KDM4E (0.59) | GAAMAPTKDM4ETDP1NPC1 | |
| SCHEMBL62942 | 0.85 | KDM4E (0.59) | GAAMAPTKDM4ETDP1NPC1 | |
| Norleucine SCHEMBL7458277 | 0.83 | NOS1 (0.39) | GAAMAPTKDM4ETDP1KMT2A | |
| Tyrosine SCHEMBL2162294 | 0.80 | SLC7A5 (0.53) | GAAKDM4ETDP1PKM | |
| SCHEMBL10533919 | 0.75 | GAA (0.36) | GAAMAPTKDM4ETDP1NPC1 | |
| SCHEMBL10587909 | 0.74 | MAPT (0.37) | GAAMAPTKDM4ETDP1NPC1 | |
| SCHEMBL27893737 | 0.74 | GSK3A (0.41) | GAAMAPTKDM4ETDP1NPC1 | |
| SCHEMBL17082991 | 0.72 | NPC1 (0.47) | GAAMAPTKDM4ETDP1NPC1 | |
| Cysteine SCHEMBL9128024 | 0.71 | DDB1 (0.44) | GAAMAPTKDM4ETDP1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788305-B1 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | UNIV COLUMBIA (US) | 2004-11-03 | — | — | EP | disclosed |
| US-6037386-A | LATEX BARRIER HAVING POLYMER MATRIX COMPRISING ZINC OXIDE OR ZINC GLUCONATE GEL IRRITANT DEACTIVATING AGENT; CONDOMS, GLOVES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2000-03-14 | — | — | US | disclosed |
| US-5965610-A | MIXTURE CONTAINING CHLORHEXIDINE GLUCONATE AND ZINC GLUCONATE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0788305-A4 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | UNIV COLUMBIA (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5708023-A | NONIRRITATING GEL FOR SKIN | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0788305-A1 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | The Trustees of Columbia University in the City of New York (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1995026134-A1 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-10-05 | — | — | WO | disclosed |