Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystine SCHEMBL440078 | 0.85 | KDM4E (0.43) | DDB1CRBNKDM4EGAAMAPT | |
| SCHEMBL746783 | 0.79 | CRBN (0.66) | DDB1CRBNKDM4EGAAMAPT | |
| SCHEMBL11849406 | 0.77 | CRBN (0.63) | DDB1CRBNKDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL31439105 | 0.77 | CRBN (0.63) | DDB1CRBNKDM4EGAAMAPT | |
| Cysteine SCHEMBL28149646 | 0.72 | PTGS1 (0.64) | PTGS1SLC7A11ALPIPKMXIAP | |
| Phthalimide SCHEMBL4392749 | 0.72 | PTGS1 (0.53) | PTGS1SLC7A11ALPIPKMXIAP | |
| Alanine SCHEMBL6904189 | 0.71 | GAA (0.45) | DDB1CRBNKDM4EGAAMAPT | |
| Cysteine SCHEMBL26928643 | 0.71 | SLC7A11 (0.61) | CRBNKDM4EMAPTTDP1PTGS1 | |
| Cysteine SCHEMBL14956977 | 0.71 | SLC7A11 (0.61) | CRBNKDM4EMAPTTDP1PTGS1 | |
| Cysteine SCHEMBL3447686 | 0.70 | SLC7A11 (0.67) | KDM4ETDP1PTGS1SLC7A11SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387673-A | Consisting of amino acids 70 to 155 of basic fibroblast growth factor; binds to heparin or heparin sepharose | AMERICAN CYANAMID COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| US-5206354-A | Shortest fragment that retains biological activity | AMERICAN CYANAMID COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0486861-A1 | Active fragments of fibroblast growth factor | AMERICAN CYANAMID COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |