SCHEMBL6904198

SCHEMBL6904198

[O]CC(CCO)n1cnc2c(-c3ccsc3)ncnc21

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 3/20 0.33
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904204 0.91 AHCY (0.34) AHCY
SCHEMBL6902586 0.84 HPRT1 (0.43) AHCY
SCHEMBL6902812 0.77 FGFR1 (0.39) AHCY
SCHEMBL6691673 0.76 AHCY (0.35) AHCY
SCHEMBL6693455 0.74 AHCY (0.36) AHCY
SCHEMBL6904115 0.71 AHCY (0.33) AHCY
SCHEMBL6905054 0.68 HPRT1 (0.45) P2RX7
SCHEMBL6324402 0.68 HPRT1 (0.35)
SCHEMBL6693196 0.66 ADORA2A (0.52) AHCY
SCHEMBL5080086 0.66 ADORA2A (0.59) AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040014722-A1 Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases BIOCRYST PHARMACEUTICALS, INC. 2004-01-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014722-A1 Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases NSUN2, POLR2H, NSUN3 AHCY 921/4885P2RX7 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.