Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698988 | 0.83 | ALDH1A1 (0.45) | AKR1B1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL2775697 | 0.82 | PTGDR2 (0.39) | CA2CA12CA1CA9 | |
| SCHEMBL12643474 | 0.79 | ESR1 (0.47) | CA2ESR1CA12CA1CA7 | |
| SCHEMBL6901530 | 0.78 | ALDH1A1 (0.49) | CA2CA12CA1CA6CA5A | |
| SCHEMBL6906601 | 0.78 | CA12 (0.40) | CA2ESR1CA12CA1TYR | |
| SCHEMBL11297196 | 0.77 | CA2 (0.46) | CA2CAMK2AESR1CA12CA1 | |
| SCHEMBL13645018 | 0.77 | CA2 (0.46) | CA2CAMK2AESR1CA12CA1 | |
| SCHEMBL22468266 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1 | |
| SCHEMBL6904226 | 0.77 | CA12 (0.49) | CA2ESR1CA12CA1CA7 | |
| SCHEMBL25362468 | 0.76 | NR4A1 (0.54) | ALDH1A1MAOBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | claimed |
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | claimed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | disclosed |
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | disclosed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | disclosed |
| EP-0137227-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES USING NOVEL THIOESTERS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-12-16 | — | — | EP | disclosed |
| EP-0047014-B1 | NOVEL THIOESTERS AND PROCESS FOR THE PREPARATION OF THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-01-15 | — | — | EP | disclosed |
| EP-0137227-A1 | Process for the preparation of cephalosporin derivatives using novel thioesters | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-04-17 | — | — | EP | disclosed |
| US-4463179-A | ACYLATION OF 7-AMINO-OR HYDRAZINO CEPHALOSPORINS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-07-31 | — | — | US | disclosed |
| US-4456754-A | ACYLATION OF CEPHALOSPORIN DERIVATIVE WITH THIOESTER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-06-26 | — | — | US | disclosed |
| US-4454323-A | 1-Methyltetrazol-5-ylthio ester of cyanomethylthioacetic acid | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0047014-A2 | Novel thioesters and process for the preparation of the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | GRHPR, ARL1, SUCLG1 | CA2 1324/4885CAMK2A 4348/4885ESR1 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.