Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724895 | 0.91 | THRB (0.43) | THRB | |
| SCHEMBL6729386 | 0.78 | THRB (0.35) | THRB | |
| SCHEMBL29133533 | 0.75 | THRB (0.60) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL64889 | 0.73 | THRB (0.94) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL20478151 | 0.73 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL28417455 | 0.73 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL1766828 | 0.73 | THRB (0.57) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL20478148 | 0.73 | THRB (0.65) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL425501 | 0.73 | THRB (0.57) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL28030131 | 0.73 | THRB (0.65) | THRBCA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737544-B1 | HEATING ABOVE MELTING POINT | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-18 | — | — | US | disclosed |