SCHEMBL425501

SCHEMBL425501

O=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.57
CA1 P00915 5/20 0.33
CA2 P00918 5/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
LMNA P02545 1/20 0.32
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL955674 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL7779621 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL953593 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL957654 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL428315 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL465610 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL7779859 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL7782672 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL536269 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2
SCHEMBL957476 0.97 THRB (0.62) THRBCA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178223-B Belzutifan and preparation method of intermediate thereof 上海皓鸿生物医药科技有限公司 2024-12-03 CN claimed
CN-118420474-A Reactive short fluorocarbon chain Gemini type cationic surfactant and preparation method thereof 三明学院 2024-08-02 CN claimed
CN-116178223-A Preparation method of Belzutifan and intermediate thereof 上海皓鸿生物医药科技有限公司 2023-05-30 CN claimed
CN-116143833-A Preparation method of phosphorus imide catalyst and application of phosphorus imide catalyst in Saucy-Marbet rearrangement reaction 万华化学集团股份有限公司 2023-05-23 CN claimed
CN-112538310-B Flexible epoxy acrylate UV curing coating and application thereof in cable joint 中电保力(北京)科技有限公司 2022-03-15 CN claimed
WO-2025121211-A1 ETCHING METHOD 株式会社レゾナック 2025-06-12 WO disclosed
WO-2025121309-A1 ETCHING METHOD 株式会社レゾナック 2025-06-12 WO disclosed
WO-2025105291-A1 METHOD FOR PRODUCING ACID FLUORIDE-FILLED CONTAINER 株式会社レゾナック 2025-05-22 WO disclosed
CN-116178223-B Belzutifan and preparation method of intermediate thereof 上海皓鸿生物医药科技有限公司 2024-12-03 CN disclosed
US-12068304-B2 Method for producing a component, and component OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2024-08-20 US disclosed
CN-118420474-A Reactive short fluorocarbon chain Gemini type cationic surfactant and preparation method thereof 三明学院 2024-08-02 CN disclosed
CN-118139839-A Process for producing fluorinated polyether 株式会社力森诺科 2024-06-04 CN disclosed
US-4358624-A FLUOROPOLYMERS; POLYCARBONATES; FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1982-11-09 US disclosed
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
WO-1982002380-A1 FLUORINATED MONOPHENOLS AND DIPHENOLS AND METHOD FOR THEIR PREPARATION GEN ELECTRIC (US) 1982-07-22 WO disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4144374-A DIRECT FLUORINATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1979-03-13 US disclosed