Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863788 | 0.84 | GAA (0.42) | CA2POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL6858246 | 0.78 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL6862641 | 0.76 | SMN1; SMN2 (0.43) | POLBSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL4206031 | 0.74 | PTGER1 (0.35) | CA2POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL6862542 | 0.73 | MTNR1A (0.43) | HPGDSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL6903617 | 0.73 | MAPT (0.52) | POLBSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL3890253 | 0.73 | MEN1 (0.51) | SMN1; SMN2GAAALDH1A1KMT2AHTR2A | |
| SCHEMBL4961897 | 0.73 | PTGER1 (0.33) | POLBHPGDSMN1; SMN2ALDH1A1GPR55 | |
| SCHEMBL3155899 | 0.73 | OPRK1 (0.39) | GAAALDH1A1 | |
| SCHEMBL27714459 | 0.72 | LTA4H (0.50) | CA2SMN1; SMN2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286957-B1 | DIPHENYLMETHANE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-11-03 | — | — | EP | disclosed |