Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 13/20 | 0.42 |
| ▸ | DRD5 | P21918 | 13/20 | 0.42 |
| ▸ | DRD2 | P14416 | 12/20 | 0.42 |
| ▸ | DRD3 | P35462 | 11/20 | 0.42 |
| ▸ | DRD4 | P21917 | 10/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905672 | 0.86 | CA2 (0.41) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL24871632 | 0.86 | CA2 (0.44) | DRD1DRD5DRD2DRD3CA2 | |
| SCHEMBL14815983 | 0.86 | DRD2 (0.40) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL6906227 | 0.75 | DRD1 (0.47) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL24604599 | 0.75 | BCL2L1 (0.50) | CA2TSHRALDH1A1TDP1GABRA1 | |
| SCHEMBL11771379 | 0.75 | BCL2L1 (0.45) | CA2TSHRALDH1A1TDP1GABRA1 | |
| SCHEMBL31379414 | 0.74 | CYP2A6 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL250734 | 0.72 | CYP2A6 (0.65) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL9419793 | 0.72 | CYP1A2 (0.46) | CYP2A6CA2TSHRALDH1A1TDP1 | |
| SCHEMBL2043313 | 0.72 | PNMT (0.49) | DRD2DRD3DRD4CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |