Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644990 | 0.91 | RORC (0.39) | RORCMMP8CA12CA1CA2 | |
| SCHEMBL13532052 | 0.86 | RORC (0.41) | RORCMMP8MEN1KMT2ANPC1 | |
| SCHEMBL925433 | 0.86 | RORC (0.41) | RORCMMP8MEN1KMT2AHPGD | |
| SCHEMBL5593182 | 0.85 | RORC (0.43) | RORCMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5084280 | 0.84 | PTGS1 (0.38) | RORCCA12CA1CA2CA7 | |
| SCHEMBL5084277 | 0.84 | PTGS1 (0.38) | RORCCA12CA1CA2CA7 | |
| SCHEMBL13532049 | 0.81 | MAPT (0.45) | RORCMEN1KMT2ANPC1HPGD | |
| SCHEMBL5747385 | 0.81 | MMP8 (0.43) | RORCMMP8MEN1KMT2ANPC1 | |
| SCHEMBL9366709 | 0.81 | MAPT (0.49) | RORCMMP8MEN1KMT2ANPC1 | |
| SCHEMBL13532054 | 0.79 | KMT2A (0.38) | RORCMEN1KMT2ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012111-A | Preparation method 2,4,5-trifluorophenylacetic acid | UNIV QUZHOU | 2013-04-03 | — | — | CN | claimed |
| CN-115246762-A | Preparation method of 2,4,5-trifluorophenylacetic acid | 上海朴颐化学科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-110642696-A | Synthetic method of 2,4, 5-trifluorophenylacetic acid | 胡婷 | 2020-01-03 | — | — | CN | disclosed |
| CN-107673951-A | A kind of high efficiency preparation method of 2,4,5 trifluoro benzene acetic acid | 河南师范大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-107522609-A | A kind of novel method for synthesizing of 2,4,5 trifluoro benzene acetic acid | 河南师范大学 | 2017-12-29 | — | — | CN | disclosed |
| CN-103012111-B | A kind of preparation method of 2,4,5-trifluoro benzene acetic acid | QUZHOU UNIVERSITY (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103012111-A | Preparation method 2,4,5-trifluorophenylacetic acid | UNIV QUZHOU | 2013-04-03 | — | — | CN | disclosed |
| CN-1197841-C | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2005-04-20 | — | — | CN | disclosed |
| EP-1002788-B1 | Process for preparing halogenated phenylmalonates | BASF AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| US-6156925-A | Process for the preparation of halogenated phenylmaloates | AMERICAN CYANAMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| EP-1002788-A1 | Process for preparing halogenated phenylmalonates | American Cyanamid Company (US) | 2000-05-24 | — | — | EP | disclosed |
| CN-1250044-A | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2000-04-12 | — | — | CN | disclosed |