Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084277 | 1.00 | PTGS1 (0.38) | PTGS1PTGS2CASP1CA12CA1 | |
| SCHEMBL6904784 | 0.84 | RORC (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5082189 | 0.81 | CES2 (0.35) | CES2CES1 | |
| SCHEMBL5082185 | 0.81 | CES2 (0.35) | CES2CES1 | |
| SCHEMBL17321034 | 0.81 | SMN1; SMN2 (0.43) | PTGS1PTGS2CASP1CES2CES1 | |
| SCHEMBL8229151 | 0.81 | CES2 (0.55) | PTGS1PTGS2CES2CES1 | |
| SCHEMBL25409627 | 0.80 | CYP3A4 (0.42) | PTGS1PTGS2CASP1CES2CES1 | |
| SCHEMBL1644990 | 0.79 | RORC (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10351810 | 0.79 | FFAR1 (0.45) | PTGS2 | |
| SCHEMBL31192692 | 0.79 | APLNR (0.42) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078350-A2 | PROCESS FOR THE PREPARATION OF FLUOROPHENYLACETIC ACIDS AND DERIVATIVES THEREOF | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2008-07-03 | — | — | WO | disclosed |