Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720148 | 0.77 | RAB9A (0.45) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6988908 | 0.74 | CCR1 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL19695 | 0.73 | TSHR (0.42) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL17784064 | 0.72 | CYP1A2 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Dipyridyl SCHEMBL28268549 | 0.72 | KDM4E (0.82) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29746183 | 0.72 | KDM4E (0.61) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29496173 | 0.72 | KDM4E (0.61) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL500395 | 0.72 | KDM4E (0.61) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| Dipyridyl SCHEMBL30649201 | 0.72 | KDM4E (0.93) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL12817468 | 0.71 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100354287-C | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with donor bridge | BASSEL POLYOLEFIN AG (DE) | 2007-12-12 | — | — | CN | claimed |
| CN-1255441-C | Process for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-05-10 | — | — | CN | claimed |
| CN-1610689-A | Cyclopentadienyl complexes with condensed heterocycles | BASELL POLYOLEFINE GMBH (DE) | 2005-04-27 | — | — | CN | claimed |
| CN-1553920-A | Method of polymerization of olefins | ��������ϩ���ɷ�����˾ | 2004-12-08 | — | — | CN | claimed |
| US-20040242880-A1 | Monocyclopentadienyl complexes comprising a condensed heterocycle | BASELL POLYOLEFINE GMBH (DE) | 2004-12-02 | — | — | US | claimed |
| CN-1310929-C | Cyclopentadienyl complexes with condensed heterocycles | BASELL POLYOLEFINE GMBH (DE) | 2007-04-18 | — | — | CN | disclosed |
| CN-1273499-C | Catalytic solid supported on calcined hydrotalcite for olefine polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2006-09-06 | — | — | CN | disclosed |
| CN-1260256-C | Catalyst solid comprising pyrogenic silica for olefin polymerization | BASELL POLYOLEFINE GMBH (DE) | 2006-06-21 | — | — | CN | disclosed |
| CN-1255441-C | Process for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-05-10 | — | — | CN | disclosed |
| CN-1231506-C | Ethylene and C3－C12Copolymers of alpha-olefins | BASSEL POLYOLEFIN AG (DE) | 2005-12-14 | — | — | CN | disclosed |
| CN-1636022-A | Catalytic solid supported on calcined hydrotalcite for olefine polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2005-07-06 | — | — | CN | disclosed |
| CN-1610689-A | Cyclopentadienyl complexes with condensed heterocycles | BASELL POLYOLEFINE GMBH (DE) | 2005-04-27 | — | — | CN | disclosed |
| CN-1604914-A | Catalyst solid comprising pyrogenic silica for olefin polymerization | BASELL POLYOLEFINE GMBH (DE) | 2005-04-06 | — | — | CN | disclosed |
| CN-1195780-C | Catalytic solid supported on calcined hydrotalcite for olefine polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2005-04-06 | — | — | CN | disclosed |
| CN-1553920-A | Method of polymerization of olefins | ��������ϩ���ɷ�����˾ | 2004-12-08 | — | — | CN | disclosed |
| EP-1456248-A1 | CATALYST SOLID COMPRISING PYROGENIC SILICA FOR OLEFIN POLYMERIZATION | Basell Polyolefine GmbH (DE) | 2004-09-15 | — | — | EP | disclosed |
| CN-1436199-A | Catalytic solid supported on calcined hydrotalcite for olefine polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2003-08-13 | — | — | CN | disclosed |
| WO-2003054027-A1 | CATALYST SOLID COMPRISING PYROGENIC SILICA FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2003-07-03 | — | — | WO | disclosed |
| CN-1399640-A | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with donor bridge | BASSEL POLYOLEFIN AG (DE) | 2003-02-26 | — | — | CN | disclosed |
| CN-1384844-A | Copolymers of ethylene with C3-C12 olefins | BASSEL POLYOLEFIN AG (DE) | 2002-12-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242880-A1 | Monocyclopentadienyl complexes comprising a condensed heterocycle | MCM4, MCM3, CCNC | KDM4E 3332/4885NPC1 3108/4885RAB9A 4232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.