Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17784064 | 0.84 | CYP1A2 (0.50) | RAB9ANPC1ARCYP1A2CYP2C9 | |
| SCHEMBL5784558 | 0.80 | KIF11 (0.39) | MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL5198932 | 0.80 | TNF (0.38) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6904790 | 0.77 | KDM4E (0.52) | RAB9AMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL27830693 | 0.76 | CTSS (0.49) | MEN1KMT2ACYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL547112 | 0.74 | ALDH1A1 (0.42) | RAB9AMEN1KMT2ANPC1AR | |
| SCHEMBL7466888 | 0.72 | RAB9A (0.62) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5788672 | 0.72 | KDM4E (0.56) | RAB9AMEN1KMT2ANPC1CYP3A4 | |
| SCHEMBL1071858 | 0.71 | CYP1A2 (0.46) | RAB9APARP1CYP1A2KDM4E | |
| SCHEMBL28928372 | 0.71 | PARP1 (0.47) | RAB9AMEN1KMT2APARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |