Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30525923 | 0.85 | PDCD1 (0.32) | L3MBTL1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6695083 | 0.83 | PDCD1 (0.31) | L3MBTL1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL218745 | 0.80 | PDCD1 (0.33) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5169306 | 0.80 | PDCD1 (0.33) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL216306 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3811780 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL966562 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5950948 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL338921 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7211643 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677411-B2 | AS CATALYST SUPPORT AN ION-EXCHANGE LAYERED SILICATE HAVING A SPECIFIC PORE SIZE DISTRIBUTION CURVE | JAPAN POLYCHEM CORPORATION (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030027950-A1 | Component of catalyst for olefin polymerization | JAPAN POLYCHEM CORPORATION (JP) | 2003-02-06 | — | — | US | disclosed |