Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL218745 | 0.82 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5169306 | 0.82 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4660461 | 0.82 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7832821 | 0.82 | KDM4E (0.32) | — | |
| Hydrochloric Acid SCHEMBL30525923 | 0.81 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4659128 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6695083 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL609949 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5950948 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3811780 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515037-B2 | A molded foam using a copolymer of propylene and an alpha-omega diene having been polymerized in the presence of a metallocene supported catalyst and foaming agent; uniform and fine foamed cells; high foaming magnification; extrusion | CHISSO CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6337372-B1 | ADDITIOIN POLYMERIZATION OF OLEFINS AND PROPYLENE FOR BLOCK POLYMERS | CHISSO CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-20010031834-A1 | Using coordination catalyst; flexibility, elasticity; molding materials | CHISSO CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-20010020045-A1 | Polypropylene base resin composition for foam-molding, foamed article using the same composition, production process for the same foamed article and foam-molded product using the foamed-article | CHISSO CORPORATION | 2001-09-06 | — | — | US | disclosed |