Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30525923 | 0.99 | PDCD1 (0.32) | PDCD1CD274CYP2A6CYP2B6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6904906 | 0.83 | L3MBTL1 (0.32) | L3MBTL1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL218745 | 0.82 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5169306 | 0.82 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL966562 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL338921 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL609949 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3811780 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5950948 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7211643 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010102-A1 | Bridged ylide group containning metal complexes | ROBERT BOSCH GMBH (DE) | 2004-01-15 | — | — | US | disclosed |
| EP-1328533-A1 | BRIDGED YLIDE GROUP CONTAINING METAL COMPLEXES | Dow Global Technologies Inc. (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034759-A1 | BRIDGED YLIDE GROUP CONTAINING METAL COMPLEXES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-05-02 | — | — | WO | disclosed |