Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913273 | 0.92 | CYP3A4 (0.41) | CYP3A4TSHRTDP1AKR1C1HSP90AA1 | |
| SCHEMBL7804096 | 0.85 | ALOX15 (0.37) | FTOALOX15ALOX12DHFRTYMS | |
| SCHEMBL6911177 | 0.80 | AKR1C1 (0.41) | CYP3A4TSHRTDP1AKR1C1HSP90AA1 | |
| SCHEMBL6911938 | 0.78 | CYP3A4 (0.39) | CYP3A4TSHRTDP1AKR1C1HSP90AA1 | |
| SCHEMBL6911622 | 0.74 | FTO (0.43) | CYP3A4TSHRTDP1AKR1C1HSP90AA1 | |
| SCHEMBL27435440 | 0.72 | CYP3A4 (0.36) | CYP3A4TSHRTDP1AKR1C1GABRA1 | |
| SCHEMBL27436182 | 0.72 | CYP3A4 (0.36) | CYP3A4TSHRTDP1AKR1C1GABRA1 | |
| SCHEMBL27432828 | 0.69 | CYP3A4 (0.38) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL4518031 | 0.67 | CYP26A1 (0.36) | FTOALOX15ALOX12 | |
| SCHEMBL6914734 | 0.67 | FTO (0.41) | TSHRTDP1AKR1C1FTOALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736574-B1 | Thermoplastic resin composition comprising carbonate and acrylic resin | GEN ELECTRIC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-0685526-B1 | Fire-resistant polycarbonate resin composition | GEN ELECTRIC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1070743-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-6103827-A | A TRANSPARENT THERMOPLASTIC RESIN BLENDS | GENERAL ELECTRIC COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-6043310-A | FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. | GENERAL ELECTRIC COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0561630-B1 | Polycarbonate resin compositions for optical use | GE PLASTICS JAPAN LTD (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5883194-A | RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS | GENERAL ELECTRIC COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0736558-A2 | A polyester polycarbonate composition which is transparent and has outstanding thermal stability | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0694582-A2 | A glass-fiber-reinforced polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0694581-A2 | A polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5418269-A | Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks | GE PLASTICS JAPAN (JP) | 1995-05-23 | — | — | US | disclosed |
| US-5403878-A | With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability | CITIBANK, N.A., AS COLLATERAL AGENT | 1995-04-04 | — | — | US | disclosed |
| US-5389713-A | Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound | GE PLASTICS JAPAN (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0605157-A2 | Resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0605194-A2 | Transparent polycarbonate-polyester-blends | GE PLASTICS JAPAN LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5276109-A | Molding materials with transparency | GENERAL ELECTRIC COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0561638-A1 | Optical-grade polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0561629-A2 | Polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0561630-A2 | Polycarbonate resin compositions for optical use | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0520806-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 1992-12-30 | — | — | EP | disclosed |