Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 4/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905063 | 0.85 | CYP3A4 (0.39) | ALOX15DHFRTYMSFTOALOX12 | |
| SCHEMBL6914734 | 0.82 | FTO (0.41) | ALOX15DHFRTYMSFTOHTR6 | |
| SCHEMBL6913273 | 0.80 | CYP3A4 (0.41) | ALOX15FTOALOX12 | |
| SCHEMBL7751772 | 0.78 | DHFR (0.40) | ALOX15DHFRTYMSFTOHTR6 | |
| SCHEMBL6911177 | 0.68 | AKR1C1 (0.41) | DHFRTYMSFTOOPRM1OPRD1 | |
| SCHEMBL11144426 | 0.68 | ALOX15 (0.36) | ALOX15DHFRTYMSALOX12HTR6 | |
| SCHEMBL7740691 | 0.68 | MEN1 (0.47) | FTOESR1ESR2 | |
| SCHEMBL4518031 | 0.67 | CYP26A1 (0.36) | ALOX15FTOALOX12 | |
| SCHEMBL6911938 | 0.67 | CYP3A4 (0.39) | ALOX15DHFRTYMSALOX12 | |
| SCHEMBL6915372 | 0.67 | BACE1 (0.41) | ALOX15DHFRTYMSHTR6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197917-B1 | Method for manufacturing polycarbonate for optical use | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |