Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | EDNRB | P24530 | 3/20 | 0.37 |
| ▸ | EDNRA | P25101 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904744 | 0.88 | ADORA2A (0.41) | ADORA2ACYP19A1LMNAMAPTCYP1A2 | |
| SCHEMBL3135177 | 0.80 | CYP1A2 (0.58) | CYP19A1LMNAMAPTCYP1A2TP53 | |
| SCHEMBL9122030 | 0.78 | ADORA2A (0.43) | ADORA2ALMNAMAPTCYP1A2TP53 | |
| SCHEMBL10933413 | 0.77 | EDNRB (0.50) | CYP19A1LMNAMAPTCYP1A2TP53 | |
| SCHEMBL25028023 | 0.73 | LMNA (0.54) | ADORA2ACYP19A1LMNAMAPTCYP1A2 | |
| SCHEMBL29642916 | 0.73 | TP53 (0.59) | CYP19A1LMNAMAPTCYP1A2TP53 | |
| SCHEMBL4937596 | 0.73 | TP53 (0.59) | CYP19A1LMNAMAPTCYP1A2TP53 | |
| SCHEMBL11481819 | 0.73 | ADORA2A (0.39) | ADORA2AMAPTPBRM1ALDH1A1KDM4E | |
| SCHEMBL9571771 | 0.73 | CYP19A1 (0.63) | CYP19A1LMNAMAPTCYP1A2TP53 | |
| SCHEMBL70993 | 0.72 | LMNA (0.54) | CYP19A1LMNAMAPTCYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |