Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905086 | 0.88 | ADORA2A (0.44) | ADORA2ALMNAMAPTCYP1A2TP53 | |
| SCHEMBL20902858 | 0.76 | HTR7 (0.43) | ADORA2ALMNAHTR2BPBRM1CACNB4 | |
| SCHEMBL9122030 | 0.72 | ADORA2A (0.43) | ADORA2ALMNAMAPTCYP1A2TP53 | |
| SCHEMBL10587799 | 0.71 | ADORA2A (0.50) | ADORA2ALMNAMAPTCYP1A2TP53 | |
| SCHEMBL6905334 | 0.69 | CACNB4 (0.41) | LMNACYP1A2TP53MAPK1PBRM1 | |
| SCHEMBL7028632 | 0.69 | PBRM1 (0.41) | ADORA2AMAPTCYP1A2MAPK1PBRM1 | |
| SCHEMBL125609 | 0.68 | NSD2 (0.55) | ADORA2ALMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL7030240 | 0.68 | ALDH1A1 (0.34) | ADORA2AMAPTHTR2BPBRM1CACNB4 | |
| SCHEMBL11481819 | 0.68 | ADORA2A (0.39) | ADORA2AMAPTPBRM1ALDH1A1KDM4E | |
| SCHEMBL7029698 | 0.67 | ALDH1A1 (0.33) | ADORA2AMAPTCYP1A2TP53PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |