Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515037 | 0.85 | ALDH1A1 (0.43) | NOS3NOS2ALDH1A1KDM4EMAPT | |
| SCHEMBL11148575 | 0.85 | ALDH1A1 (0.41) | NOS3NOS2ALDH1A1KDM4EMAPT | |
| SCHEMBL3025730 | 0.83 | DHFR (0.36) | NOS3NOS2ALDH1A1KDM4EMAPT | |
| SCHEMBL10432144 | 0.79 | DHFR (0.36) | NOS3NOS2ALDH1A1KDM4EMAPT | |
| SCHEMBL25162110 | 0.79 | ALDH1A1 (0.48) | NOS3NOS2ALDH1A1KDM4EMAPT | |
| SCHEMBL395488 | 0.77 | DHFR (0.42) | NOS3NOS2ALDH1A1MAPTGAA | |
| SCHEMBL18966864 | 0.76 | KMT2A (0.40) | NOS3NOS2ALDH1A1KDM4ENOS1 | |
| SCHEMBL394710 | 0.76 | NOS3 (0.39) | NOS3NOS2ALDH1A1MAPTNOS1 | |
| SCHEMBL29348122 | 0.76 | NOS3 (0.36) | NOS3NOS2ALDH1A1KDM4EMAPT | |
| SCHEMBL11230051 | 0.76 | CYP3A4 (0.35) | NOS3NOS2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762273-B2 | DURABILITY; AERODYNAMIC SURFACE GEOMETRY; REACTION PRODUCT OF POLYTETRAMETHYLENE ETHER GLYCOL TERMINATED TOLUENE DIISO-CYANATE, N,N'-DIALKYLAMINO-DIPHENYL-METHANE AND 4,4''-METHYLENEBIS-(2,6-DIETHYL)-ANILINE | CALLAWAY GOLF COMPANY | 2004-07-13 | — | — | US | disclosed |
| US-20040116622-A1 | [A THERMOSETTING POLYURETHANE MATERIAL FOR A GOLF BALL COVER] | CALLAWAY GOLF COMPANY (US) | 2004-06-17 | — | — | US | disclosed |
| US-20030228937-A1 | Thermosetting polyurethane material for a golf ball cover | CALLAWAY GOLF COMPANY | 2003-12-11 | — | — | US | disclosed |