SCHEMBL6905737

SCHEMBL6905737

Fc1ccc2c(c1F)Cc1c(F)ccc(F)c1C2

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.31
HTR2A P28223 1/20 0.31
HTR2B P41595 1/20 0.31
PGR P06401 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142423 0.70 CYP2A6 (0.42) HTR2CHTR2AHTR2B
SCHEMBL14538503 0.69
SCHEMBL23591519 0.67 CYP3A4 (0.31)
SCHEMBL1912510 0.67
SCHEMBL5866469 0.67 CES2 (0.32)
SCHEMBL1249690 0.67 CES1 (0.42) HTR2CHTR2AHTR2B
SCHEMBL10534995 0.66
SCHEMBL9811068 0.66 PNMT (0.46) HTR2CHTR2AHTR2BPGR
SCHEMBL11442862 0.65 HTR2C (0.40) HTR2CHTR2AHTR2BCHRNB2CHRNB4
SCHEMBL4756408 0.65 CES1 (0.41) HTR2CHTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed